Glyceryl Trinitrate (GTN) Spray

What is GTN?

  • GTN Spray is commonly used to treat angina, a condition characterised by chest pain or discomfort.

  • It belongs to the class of drugs known as nitrates.

How Does it Work and Why is it Important to Take?

  • GTN Spray relaxes and widens blood vessels, especially around the heart. This boosts blood flow to the heart muscle, easing angina symptoms and reducing heart strain.

  • Taking it as prescribed is vital for symptom relief and better heart blood flow

The Dose of The Medication

  • Use 1 or 2 sprays under your tongue

  • You can have a second dose of 1 or 2 sprays under your tongue if they pain still persists after 5 mines of the first dose

How to Take It

  • Sit down comfortably.

  • Remove the cap and place your finger on the button.

  • Prime the spray by spraying it into the air.

  • Hold the spray in front of you and take a deep breath.

  • Open your mouth and lift your tongue to the roof.

  • While holding your breath, press the button to spray.

  • Close your mouth and breathe in through your nose.

  • If needed, repeat the steps for another dose.

  • Remain seated for 5 minutes, then rise slowly when ready."

What to Expect

  • GTN Spray offers rapid relief from angina symptoms, typically within minutes of use. Its effects are short-lived, lasting around 20 to 30 minutes.

Possible Side Effects

  • Nausea

  • Dizziness and weakness

  • Tired or drowsy

  • Headaches

  • Flushing

Management of Side Effects

  • Click here for common side effects and how to manage them

  • If you experience severe, persistent or bothersome side effects, contact your GP clinician, local pharmacy or NHS 111

Common Interactions

  • Inform your clinician about all medications, including over-the-counter and herbal supplements, as they can interact with GTN.

  • This includes erectile dysfunction drugs like sildenafil, tadalafil, etc.

  • Avoid over-the-counter ibuprofen or aspirin unless advised by a clinician.

Special Warnings

  • Call 999 if, five minutes after your second dose, pain persists, worsens, or you feel unwell.

  • Limit alcohol intake to reduce medication side effects.

Monitoring Your Progress

  • Your GP clinician may monitor your blood pressure and adjust the treatment plan accordingly

  • Keep track of your angina symptoms and report any changes to your GP clinician

Where to Find More Information and Who to Contact

  • Refer to the patient information leaflet and the NHS website for more details.

  • If you have questions or experience unusual symptoms, contact your GP clinician, local pharmacy, or NHS 111.