Amitritypline

Brand Names of Amitriptyline: Elavil, Endep, Vanatrip, Amitrol, Tryptizol

What is Amitriptyline?

  • Amitriptyline is a medication widely used to alleviate depression, anxiety, nerve pain, and migraines.

  • It belongs to the class of drugs known as tricyclic antidepressants.

How Does it Work and Why is it Important to Take?

  • Amitriptyline works by rebalancing chemicals in the brain, specifically serotonin and noradrenaline.

  • Maintaining this balance is crucial for effectively managing mood disorders and certain types of pain.

The Dose of The Medication

  • Your Amitriptyline dose is personalised based on your condition and response.

  • Typically, you'd start with 10mg daily, adjusted by your clinician for better pain control.

  • The maximum daily dose for pain relief is 75mg, with higher doses for conditions like migraine prevention and depression.

How and When to Take It

  • Take Amitriptyline before bedtime to minimise drowsiness.

What to Expect

  • Patience is vital; you might start feeling better after 1-2 weeks, but full effects may take around 6 weeks.

What to Do if You Miss a Dose

  • If you forget a dose, take it as soon as you remember.

  • If it's near your next scheduled dose, skip the missed one—never double up.

Possible Side Effects

  • Drowsiness

  • Dizziness

  • Dry mouth

  • Constipation

  • Difficulty urinating

  • Headaches

Management of Side Effects

  • Click here for common side effects and how to manage them

  • If still drowsy the next day, consider taking Amitriptyline a bit earlier.

  • Some side effects improve as your body adjusts.

  • For severe, persistent, or bothersome side effects, consult your GP clinician, local pharmacy, or NHS 111.

Common Interactions

  • Keep your clinician informed about all medications, including over-the-counter and herbal supplements.

  • St John’s Wort, an herbal remedy for depression, may interact with Amitriptyline.

Special Warnings

  • Moderate alcohol while on Amitriptyline to avoid enhanced drowsiness.

  • Be cautious in the sun, as sensitivity may increase.

  • Do not abruptly stop treatment to prevent withdrawal symptoms; consult your GP clinician.

Monitoring Your Progress

  • Regular check-ups with your GP clinician are crucial for monitoring progress, adjusting your treatment plan, and addressing concerns.

Where to Find More Information and Who to Contact

  • Refer to the patient information leaflet and the NHS website for more details.

  • If you have questions or experience unusual symptoms, contact your GP clinician, local pharmacy, or NHS 111.