Gliclazide

What is Gliclazide?

  • Gliclazide helps manage blood sugar levels in type 2 diabetes.

  • It's part of a group of drugs called sulfonylureas.

How Does it Work and Why is it Important to Take?

  • Gliclazide stimulates the pancreas to release insulin, which regulates blood sugar.

  • It's crucial for controlling diabetes and lowering elevated blood sugar levels, reducing the risk of complications like heart disease and kidney problems.

The Dose of The Medication

  • The starting dose varies.

  • For standard release, the maximum is 320mg a day, often split into two doses if over 160mg.

  • For modified release, the maximum is 120mg a day.

How and When to Take It

  • Take Gliclazide with food.

  • If once daily, take it with breakfast. If twice daily, take it with breakfast and dinner.

What to Expect

  • Gliclazide may not show immediate symptoms, but continue taking it.

What to Do if You Miss a Dose

  • Skip the missed dose and take the next scheduled one. Never double up.

Possible Side Effects

  • Stomach pain

  • Indigestion

  • Diarrhoea

  • Nausea and vomiting

  • Constipation

  • Weight gain

  • Low blood sugar levels

Management of Side Effects

  • Click here for common side effects and how to manage them.

  • Some side effects improve as your body adjusts.

  • If severe, persistent or bothersome side effects occur, consult your GP, local pharmacy, or NHS 111.

Common Interactions

  • Inform your clinician about all medications, including over-the-counter and herbal supplements.

  • St. John’s Wort can affect Gliclazide.

  • Check with your GP clinician before taking ibuprofen or aspirin.

Special Warnings

  • Limit alcohol intake to 14 units a week, as it can affect blood sugar control

  • Signs of low blood sugar include feeling hungry, shaking, trembling, sweating, confusion, difficulty concentrating, etc. If this happens to you, then have fast-acting sugars like sugar juice or you may need to have a meal. If your symptoms have not improved call your GP practice or NHS 111

Monitoring Your Progress

  • Regular check-ups with your healthcare provider are important for blood sugar monitoring and adjusting medication.

Where to Find More Information and Who to Contact

  • Refer to the patient information leaflet and the NHS website for more details.

  • If you have questions or experience unusual symptoms, contact your GP clinician, local pharmacy, or NHS 111.