Omeprazole

What is Omeprazole?

  • Omeprazole is a medication commonly prescribed to reduce stomach acid production, offering relief for conditions like acid reflux, heartburn, and stomach ulcers.

  • It belongs to the class of drugs known as Proton Pump Inhibitors (PPIs), which can also protect the stomach from certain medications or combination of medications.

How Does it Work and Why is it Important to Take?

  • Omeprazole works by inhibiting the proton pump in the stomach lining, which reduces acid production.

  • This helps prevent and heal conditions like acid reflux and ulcers, providing relief and safeguarding the digestive system.

The Dose of The Medication

  • The usual starting dose of omeprazole is 10mg to 40mg a day, with a maximum daily dose of up to 120mg, taken in divided doses.

How and When to Take It

  • It is usually best to take omeprazole in the morning. If prescribed once a day, take it before breakfast. If prescribed twice a day, take it in the morning and evening.

What to Expect

  • Omeprazole may start providing relief within a few days, but it may take up to a month to work properly.

What to Do if You Miss a Dose

  • If you miss a dose of Lansoprazole:

    • For once-a-day dosing: Take it as soon as you remember if it's within 12 hours of your next dose. If it's closer to your next dose, skip the missed one and continue as usual.

    • For twice-a-day dosing: Take it as soon as you remember if it's within 4 hours of your next dose. If it's closer to your next dose, skip the missed one and continue as usual.

  • Never take double doses to make up for a missed one.

Possible Side Effects

  • Headaches

  • Nausea and vomiting

  • Stomach pain

  • Wind

  • Constipation

Management of Side Effects

  • Click here for common side effects and how to manage them.

  • Avoid certain foods that can worsen wind if it affecting you.

  • Some side effects improve as your body adjusts.

  • If severe, persistent or bothersome side effects occur, consult your GP, local pharmacy, or NHS 111.

Common Interactions

  • Inform your clinician or pharmacist if purchasing over-the-counter (OTC) about all medications you are taking, including over-the-counter and herbal supplements.

  • Avoid St John’s Wort, a herbal remedy for depression.

Special Warnings

  • Omeprazole can mask signs of more serious conditions. If you experience weight loss or swallowing difficulty, speak to your GP clinician.

  • Joint pain with a red skin rash may indicate lupus erythematosus. Consult your GP clinician or NHS 111.

  • If your skin becomes yellow and/or urine becomes darker, speak to your GP clinician or NHS 111 as it could be a sign of liver problems.

  • Long-term use of omeprazole is associated with weakened bones, electrolyte disturbances, and an increased risk of stomach infections.

  • Don't abruptly stop long-term Lansoprazole use; consult your GP clinician for guidance on safe discontinuation to avoid increased stomach acid and potential harm

Monitoring Your Progress

  • Regular check-ups with your GP clinician may be necessary to monitor your response to the medication and ensure there are no adverse effects.

  • If you have purchased omeprazole over-the-counter and your symptoms are not relieved in 14 days, you should see your GP clinician.

Where to Find More Information and Who to Contact

  • Refer to the patient information leaflet and the NHS website for more details.

  • If you have questions or experience unusual symptoms, contact your GP clinician, local pharmacy, or NHS 111.