Sitagliptin

What is Sitagliptin?

  • Sitagliptin helps manage blood sugar levels in individuals with type 2 diabetes.

  • It belongs to the class of drugs called dipeptidyl peptidase-4 (DPP-4) inhibitors.

How Does it Work and Why is it Important to Take?

  • Sitagliptin stimulates insulin release from the pancreas and reduces liver sugar production.

  • It is essential for stable blood sugar levels and effective diabetes control.

The Dose of The Medication

  • The typical dose of Sitagliptin is 100mg per day.

  • Your clinician may adjust the dose based on your kidney function.

How and When to Take It

  • Sitagliptin is usually taken once daily, at any time during the day.

  • Essential to take it at the same time daily for consistency and routine.

What to Expect

  • Sitagliptin may not produce noticeable symptoms, but it's essential to continue taking it as prescribed.

  • Its effects can begin within hours, but consistent usage is necessary for long-term management.

What to Do if You Miss a Dose

  • If you forget a dose, take it when you remember.

  • If it's close to your next scheduled dose, skip the missed one—never double up.

Possible Side Effects

  • Headaches

Management of Side Effects

  • Click here for common side effects and how to manage them.

  • Some side effects improve as your body adjusts.

  • If severe, persistent or bothersome side effects occur, consult your GP, local pharmacy, or NHS 111.

Common Interactions

  • Inform your clinician about all medications, including over-the-counter and herbal supplements.

Special Warnings

  • Limit alcohol intake to 14 units per week, as it can affect blood sugar control.

  • Sitagliptin may cause pancreatitis; seek medical attention if you experience severe stomach pains.

  • While Sitagliptin typically doesn't cause low blood sugar, when taken with other diabetic drugs, it may contribute to hypoglycemia. Symptoms include hunger, shaking, sweating, confusion, and difficulty concentrating. In such cases, consume fast-acting sugars like sugar juice or have a meal. If symptoms persist, contact your GP or NHS 111.

Monitoring Your Progress

  • Regular check-ups with your GP clinician are essential to monitor blood sugar levels, and evaluate potential side effects

Where to Find More Information and Who to Contact

  • Refer to the patient information leaflet and the NHS website for more details.

  • If you have questions or experience unusual symptoms, contact your GP clinician, local pharmacy, or NHS 111.