Spironolactone

What is Spironolactone?

  • Spironolactone is commonly prescribed to manage conditions related to high blood pressure, heart failure, and fluid buildup.

  • It belongs to the class of drugs known as diuretics, often called ‘water tablets‘.

How Does it Work and Why is it Important to Take?

  • Spironolactone helps the kidneys remove excess water and salt from the body.

  • Taking spironolactone is crucial for managing conditions associated with fluid retention and hypertension.

The Dose of The Medication

  • The dose varies depending on the reason for taking spironolactone.

How and When to Take It

  • Usually taken once a day in the morning.

  • Some may take it on alternate days.

  • High doses may require morning and early afternoon doses to avoid nighttime urination disturbances.

What to Expect

  • For fluid buildup, spironolactone may work within a few days, but it could take longer.

  • For hypertension, it may take up to a couple of weeks to see the full effect.

What to Do if You Miss a Dose

  • If you miss a dose after 4 pm, take it when you remember.

  • If it's after 4 pm, skip the dose and take the next one as usual.

  • Never double up on doses to compensate for a missed one.

Possible Side Effects

  • Increased urination (thats how it works)

  • Dizziness

  • Tiredness

  • Muscle or leg craps

  • Nausea and vomiting

  • Breast pain and breast enlargement, including men

Management of Side Effects

  • Click here for common side effects and how to manage them.

  • Consult your GP clinician or NHS 111 if you experience unexplained muscle cramps.

  • If severe, persistent or bothersome side effects occur, consult your GP, local pharmacy, or NHS 111.

Common Interactions

  • Inform your clinician about all medications, including over-the-counter and herbal supplements.

  • Avoid over-the-counter ibuprofen or aspirin unless advised by a clinician.

Special Warnings

  • Men experiencing erectile dysfunction or breast changes should consult their GP clinician.

  • Be cautious of potassium-containing foods and products, including low-sodium salts, salt alternatives, bananas, and salmon.

  • Limit alcohol intake to no more than 2 units a day, especially if taking spironolactone for liver disease.

  • Dehydration can affect kidney function; if you experience vomiting or diarrhea, follow 'Sick Day Rules' here.

Monitoring Your Progress

  • Regular check-ups, including blood pressure monitoring and potassium level checks, may be necessary. Report any significant changes in your health promptly.

Where to Find More Information and Who to Contact

  • Refer to the patient information leaflet and the NHS website for more details.

  • If you have questions or experience unusual symptoms, contact your GP clinician, local pharmacy, or NHS 111.